INFECTIVE ENDOCARDITIS IN A ONCOLOGY PATIENT: Treatment with Tricuspid Valve Replacement Using a Porcine Xenograft
INFECTIVE ENDOCARDITIS IN A ONCOLOGY PATIENT: Treatment with Tricuspid Valve Replacement Using a Porcine Xenograft
DOI:
https://doi.org/10.61229/mpj.v2i2.44Keywords:
Endocardite, cirurgia cardiovascular, câncerAbstract
Infective endocarditis (IE) of the tricuspid valve is a rare condition associated with high morbidity and mortality. It is mainly caused by the bacterium Staphylococcus aureus, which affects the heart valves and other endothelial tissues of the heart, leading to the formation of vegetations causing severe complications such as valve insufficiency. This case report describes a 33-year-old patient with uterine cancer and probable lung metastasis who developed infective endocarditis on the tricuspid valve due to Staphylococcus aureus. Despite antimicrobial treatment, the patient developed severe tricuspid insufficiency. Tricuspid valve replacement with a porcine xenograft was performed. Diagnosis was confirmed by transesophageal echocardiography, revealing significant vegetations on the valve. The surgical intervention involved removal of the vegetations and implantation of the xenograft, resulting in stable clinical recovery. This case underscores the complexity of managing infective endocarditis in oncology patients.
Downloads
References
Rajani R, Klein JL. Infective endocarditis: A contemporary update. Clin Med [Internet]. 2020 Jan;20(1):31–5. doi: 10.7861/clinmed.cme.20.1.1. DOI: https://doi.org/10.7861/clinmed.cme.20.1.1
Chahoud J, Sharif Yakan A, Saad H, Kanj SS. Right-Sided Infective Endocarditis and Pulmonary Infiltrates. Cardiol Rev [Internet]. 2016;24(5):230–7. doi: 10.1097/CRD.0000000000000095. DOI: https://doi.org/10.1097/CRD.0000000000000095
Rodger L, Glockler-Lauf SD, Shojaei E, Sherazi A, Hallam B, Koivu S, et al. Clinical Characteristics and Factors Associated With Mortality in First-Episode Infective Endocarditis Among Persons Who Inject Drugs. JAMA Netw Open [Internet]. 2018 Nov 21;1(7):e185220. doi: 10.1001/jamanetworkopen.2018.5220. DOI: https://doi.org/10.1001/jamanetworkopen.2018.5220
Iung B. [Infective endocarditis. Epidemiology, pathophysiology and histopathology]. Presse Med [Internet]. 2019 May 1;48(5):513–21. doi: 10.1016/j.lpm.2019.04.009. DOI: https://doi.org/10.1016/j.lpm.2019.04.009
Yuan SM. Right-sided infective endocarditis: recent epidemiologic changes. Int J Clin Ex Med [Internet]. 2014;7(1):199–218.
Prendergast BD. Diagnostic criteria and problems in infective endocarditis. Heart [Internet]. 2004 Jun 1;90(6):611–3. doi: 10.1136/hrt.2003.029850. DOI: https://doi.org/10.1136/hrt.2003.029850
Baddour LM, Wilson WR, Bayer AS, Fowler VG, Tleyjeh IM, Rybak MJ, et al. Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association. Circulation [Internet]. 2015;132(15):1435–86. doi: 10.1161/CIR.0000000000000296. DOI: https://doi.org/10.1161/CIR.0000000000000296
Mularoni A, Malgorzata Mikulska, Barbera F, Graziano E, Alice Annalisa Medaglia, Daniele Di Carlo, et al. Molecular Analysis With 16S rRNA PCR/Sanger Sequencing and Molecular Antibiogram Performed on DNA Extracted From Valve Improve Diagnosis and Targeted Therapy of Infective Endocarditis: A Prospective Study. Clin Infect Dis [Internet]. 2022 Jun 10 [cited 2024 Mar 13];76(3):e1484–91. doi: 10.1093/cid/ciac452. DOI: https://doi.org/10.1093/cid/ciac452
Neves Junior MA das, Melo RC, Goes Junior AM de O, Protta TR, Almeida CC de, Fernandes AR, et al. Infecções em cateteres venosos centrais de longa permanência: revisão da literatura. J Vasc Bras [Internet]. 2010;9(1):46–50. doi: 10.1590/S1677-54492010000100008. DOI: https://doi.org/10.1590/S1677-54492010000100008
Shmueli H, Thomas F, Flint N, Setia G, Janjic A, Siegel RJ. Right‐Sided Infective Endocarditis 2020: Challenges and Updates in Diagnosis and Treatment. J Am Heart Assoc [Internet]. 2020 Jul 23;9(15). doi: 10.1161/JAHA.120.017293. DOI: https://doi.org/10.1161/JAHA.120.017293
Awad AK, Wilson K, Elnagar MA, Elbadawy MA, Fathy MH. To repair or to replace in mitral valve infective endocarditis? an updated meta-analysis. J Cardiothorac Surg [Internet]. 2024;19. doi: 10.1186/s13019-024-02767-y. DOI: https://doi.org/10.1186/s13019-024-02767-y
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Mário Penna Journal
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Autores que publicam nesta revista concordam com os seguintes termos:
- Declaro que o presente artigo é original, não tendo sido submetido à publicação em qualquer outro periódico nacional ou internacional, quer seja em parte ou em sua totalidade.
- Declaro, ainda, que uma vez publicado na revista Mário Penna Journal, editada pelo Instituto Mário Penna, o mesmo jamais será submetido por mim ou por qualquer um dos demais co-autores, caso haja, a qualquer outro periódico.
- Por meio deste instrumento, em meu nome e em nome dos demais co-autores, porventura existentes, cedo os direitos autorais do referido artigo ao Instituto Mário Penna e declaro estar ciente de que a não observância deste compromisso submeterá o infrator a sanções e penas previstas na Lei de Proteção de Direitos Autorias (Nº9609, de 19/02/98).
A Revista Mário Penna Journal é licenciada sob uma licença Creative Commons Atribuição-NãoComercial-CompartilhaIgual 4.0 Internacional
